In patients with chronic hepatitis C virus (HCV) infection, the failure to achieve a sustained virologic response (SVR) 24 weeks after completing interferon therapy is a major risk factor for developing hepatocellular carcinoma (HCC). While pretreatment factors influencing HCC incidence are well-documented, there is limited understanding of the post-treatment factors, which can change during interferon therapy.
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Oze, Tsugiko, et al. "Post-treatment levels of α-fetoprotein predict incidence of hepatocellular carcinoma after interferon therapy." Clinical Gastroenterology and Hepatology 12.7 (2014): 1186-1195.
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